Negative PCR result AND detection of IgG or total antibody, in the absence of vaccination.Detection of SARS-CoV-2 by polymerase chain reaction (PCR) on two specimens at least 24 hours apart with high Ct values 3 on both specimens AND detection of IgG or total antibody, in the absence of vaccination.Previous (prior to the past 14 days) epidemiological evidence.Ī historical case should not have any symptoms of COVID-19 (or not have had symptoms of COVID-19 for the past 14 days).A historical case requires laboratory suggestive evidence supported by either previous (prior to the past 14 days) clinical evidence.SARS-CoV-2 IgG seroconversion or a four-fold or greater increase in SARS-CoV-2 antibodies of any immunoglobulin subclass including ‘total’ assays in acute and convalescent sera, in the absence of vaccination.Isolation of SARS-CoV-2 in cell culture, with confirmation using a nucleic acid test.
Detection of SARS-CoV-2 by nucleic acid testing.Case definitions Confirmed caseĪ confirmed case requires laboratory definitive evidence. settings with a high risk of transmission.Ĭlinical judgement and reasoning should be used, including consideration of epidemiological risk factors for acquisition and transmission.people who are most at risk of severe illness.People in the following groups should be tested if they have new onset of other clinical symptoms associated with COVID-19 (including headache, myalgia, stuffy nose, nausea, vomiting or diarrhoea): **Older people may present with other atypical symptoms including functional decline, delirium, exacerbation of underlying chronic condition, falls, loss of appetite, malaise, nausea, diarrhoea and myalgia. *Clinical discretion applies consider potential for co-infection (such as SARS-CoV-2 and influenza). Acute respiratory infection (including cough, sore throat, shortness of breath, runny nose)**.
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